Taurine and tea polyphenols combination ameliorate nonalcoholic steatohepatitis.

A new study published in the BMC Complementary and Alternative Medicine explored the effects of taurine, tea polyphenols (TPs) or its combination, on nonalcoholic steatohepatitis (NASH) rats. The results showed that taurine treatment alleviated hepatocyte damage and oxidative stress. While TPs treatment improved lipid metabolism and increased hepatic antioxidant activity. Furthermore, the therapeutic effects of taurine + TPs treatment on hepatocyte damage, lipid disturbance, and oxidative stress were superior to those of taurine and TPs treatments. In addition, taurine, TPs, and their combination decreased serum lipopolysaccharide levels in NASH rats; the combination therapy caused these levels to decrease more significantly than taurine or TPs treatment alone. Thus, it was inferred that taurine combined with TPs treatment could relieve NASH by alleviating hepatocyte damage, decreasing oxidative stress, and improving lipid metabolism and gut flora disturbance. It was proposed that taurine and TPs combination may act as a new effective medicine for treating NASH patients.

Reference1. Zhu W, Chen S, Chen R, Peng Z, Wan J, Wu B. Taurine and tea polyphenols combination ameliorate nonalcoholic steatohepatitis in rats. BMC Complementary and Alternative Medicine. 2017;17(1):455. doi:10.1186/s12906-017-1961-3.